FEDRATINIB for Off label use: Side Effects & Safety Data
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There are 56 adverse event reports in the FDA FAERS database where FEDRATINIB was used for Off label use.
Most Reported Side Effects for FEDRATINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 143 | 10.2% | 13 | 28 |
| Death | 138 | 9.8% | 138 | 3 |
| Nausea | 114 | 8.1% | 0 | 13 |
| Fatigue | 105 | 7.5% | 0 | 10 |
| Vomiting | 74 | 5.3% | 10 | 20 |
| Constipation | 59 | 4.2% | 9 | 18 |
| Platelet count decreased | 48 | 3.4% | 0 | 10 |
| Asthenia | 47 | 3.4% | 2 | 14 |
| Haemoglobin decreased | 46 | 3.3% | 1 | 12 |
| Full blood count decreased | 45 | 3.2% | 0 | 14 |
| Drug ineffective | 42 | 3.0% | 0 | 1 |
| Anaemia | 41 | 2.9% | 1 | 11 |
| Off label use | 40 | 2.9% | 7 | 6 |
| Dizziness | 37 | 2.6% | 0 | 8 |
| Illness | 34 | 2.4% | 1 | 6 |
Other Indications for FEDRATINIB
Myelofibrosis (682)
Product used for unknown indication (307)
Myeloproliferative neoplasm (146)
Primary myelofibrosis (77)
Polycythaemia vera (69)
Essential thrombocythaemia (28)
Myelodysplastic syndrome (27)
Splenomegaly (11)
Hairy cell leukaemia (9)
Thrombocytosis (8)
Other Drugs Used for Off label use
LENALIDOMIDE (5,767)
ECULIZUMAB (3,550)
CERTOLIZUMAB PEGOL (2,256)
ABOBOTULINUMTOXINA (2,170)
LEVETIRACETAM (2,161)
APREMILAST (1,995)
PROPRANOLOL (1,576)
CETIRIZINE (1,416)
HUMAN IMMUNOGLOBULIN G (1,129)
THALIDOMIDE (1,033)