Does LAMIVUDINE Cause Macrocephaly? 34 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 34 reports of Macrocephaly have been filed in association with LAMIVUDINE (Lamivudine and Zidovudine). This represents 0.2% of all adverse event reports for LAMIVUDINE.
34
Reports of Macrocephaly with LAMIVUDINE
0.2%
of all LAMIVUDINE reports
19
Deaths
2
Hospitalizations
How Dangerous Is Macrocephaly From LAMIVUDINE?
Of the 34 reports, 19 (55.9%) resulted in death, 2 (5.9%) required hospitalization.
Is Macrocephaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMIVUDINE. However, 34 reports have been filed with the FAERS database.
What Other Side Effects Does LAMIVUDINE Cause?
Foetal exposure during pregnancy (1,905)
Virologic failure (1,894)
Drug resistance (1,889)
Pathogen resistance (1,733)
Viral mutation identified (1,631)
Treatment failure (933)
Exposure during pregnancy (846)
Drug interaction (744)
Drug ineffective (726)
Immune reconstitution inflammatory syndrome (625)
What Other Drugs Cause Macrocephaly?
LAMIVUDINE\ZIDOVUDINE (40)
NEVIRAPINE (37)
DICLOFENAC (33)
IBUPROFEN (29)
LEVOTHYROXINE (26)
ACETAMINOPHEN (25)
LYNESTRENOL (25)
OMEPRAZOLE (25)
VALPROATE (23)
ABACAVIR (20)
Which LAMIVUDINE Alternatives Have Lower Macrocephaly Risk?
LAMIVUDINE vs LAMIVUDINE\NEVIRAPINE\ZIDOVUDINE
LAMIVUDINE vs LAMIVUDINE\TENOFOVIR
LAMIVUDINE vs LAMIVUDINE\TENOFOVIR DISOPROXIL
LAMIVUDINE vs LAMIVUDINE\ZIDOVUDINE
LAMIVUDINE vs LAMOTRIGINE