Macrocephaly: Which Medications Cause It? (256 Reports Across 39 Drugs)
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Macrocephaly has been reported as an adverse event with 39 different drugs in the FDA's FAERS database, with 256 total reports. 44 of these reports resulted in death.The drugs most commonly associated with Macrocephaly are LAMIVUDINE\ZIDOVUDINE, NEVIRAPINE, and LAMIVUDINE.
256
Total Reports
39
Drugs Involved
44
Deaths
44
Hospitalizations
8.9 yrs
Average Patient Age
32.7% / 67.3%
Female / Male
Which Drugs Cause Macrocephaly Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| LAMIVUDINE\ZIDOVUDINE | 40 | 1.5% | 20 | 0 | 0 |
| NEVIRAPINE | 37 | 0.6% | 20 | 0 | 0 |
| LAMIVUDINE | 34 | 0.2% | 19 | 2 | 0 |
| DICLOFENAC | 33 | 0.0% | 0 | 1 | 0 |
| IBUPROFEN | 29 | 0.0% | 0 | 0 | 0 |
| LEVOTHYROXINE | 26 | 0.0% | 0 | 1 | 1 |
| ACETAMINOPHEN | 25 | 0.0% | 0 | 0 | 0 |
| LYNESTRENOL | 25 | 62.5% | 0 | 0 | 0 |
| OMEPRAZOLE | 25 | 0.0% | 0 | 0 | 0 |
| VALPROATE | 23 | 0.1% | 0 | 10 | 0 |
| ABACAVIR | 20 | 0.5% | 19 | 0 | 0 |
| ASPIRIN | 20 | 0.0% | 20 | 0 | 0 |
| ABACAVIR\LAMIVUDINE | 19 | 0.4% | 19 | 0 | 0 |
| CHOLECALCIFEROL | 19 | 0.2% | 19 | 0 | 0 |
| ZIDOVUDINE | 19 | 0.3% | 1 | 4 | 0 |
| LABETALOL\LABETALOL | 18 | 0.8% | 18 | 0 | 0 |
| NIFEDIPINE | 18 | 0.2% | 18 | 0 | 0 |
| ERGOCALCIFEROL | 17 | 0.3% | 17 | 0 | 0 |
| LOPINAVIR\RITONAVIR | 16 | 0.2% | 0 | 2 | 0 |
| TENOFOVIR DISOPROXIL | 16 | 0.1% | 0 | 2 | 0 |