Does LAMOTRIGINE Cause Hyperpyrexia? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Hyperpyrexia have been filed in association with LAMOTRIGINE (Lamotrigine ER). This represents 0.1% of all adverse event reports for LAMOTRIGINE.
27
Reports of Hyperpyrexia with LAMOTRIGINE
0.1%
of all LAMOTRIGINE reports
4
Deaths
21
Hospitalizations
How Dangerous Is Hyperpyrexia From LAMOTRIGINE?
Of the 27 reports, 4 (14.8%) resulted in death, 21 (77.8%) required hospitalization, and 4 (14.8%) were considered life-threatening.
Is Hyperpyrexia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMOTRIGINE. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does LAMOTRIGINE Cause?
Drug ineffective (5,175)
Seizure (3,459)
Toxicity to various agents (3,256)
Rash (3,249)
Foetal exposure during pregnancy (2,985)
Off label use (2,625)
Completed suicide (2,433)
Drug reaction with eosinophilia and systemic symptoms (2,235)
Dizziness (2,170)
Pyrexia (1,967)
What Other Drugs Cause Hyperpyrexia?
TRASTUZUMAB (146)
RITUXIMAB (139)
CYCLOPHOSPHAMIDE (133)
PACLITAXEL (100)
ZOLEDRONIC ACID (96)
OXALIPLATIN (94)
CARBOPLATIN (73)
GEMCITABINE (72)
VINCRISTINE (69)
DABRAFENIB (68)
Which LAMOTRIGINE Alternatives Have Lower Hyperpyrexia Risk?
LAMOTRIGINE vs LANADELUMAB
LAMOTRIGINE vs LANADELUMAB-FLYO
LAMOTRIGINE vs LANREOTIDE
LAMOTRIGINE vs LANSOPRAZOLE
LAMOTRIGINE vs LANTHANUM