Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Hyperpyrexia: Which Medications Cause It? (3,028 Reports Across 231 Drugs)

Boost Your Natural Energy & Metabolism

Mitolyn — 6 exotic plants to unlock your body's fat-burning power. 90-day guarantee.

Try Mitolyn Now

Hyperpyrexia has been reported as an adverse event with 231 different drugs in the FDA's FAERS database, with 3,028 total reports. 199 of these reports resulted in death.The drugs most commonly associated with Hyperpyrexia are TRASTUZUMAB, RITUXIMAB, and CYCLOPHOSPHAMIDE.

3,028
Total Reports
231
Drugs Involved
199
Deaths
1,269
Hospitalizations
53.2 yrs
Average Patient Age
53.7% / 46.3%
Female / Male

Which Drugs Cause Hyperpyrexia Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
TRASTUZUMAB 146 0.3% 1 37 7
RITUXIMAB 139 0.1% 9 44 3
CYCLOPHOSPHAMIDE 133 0.1% 9 92 38
PACLITAXEL 100 0.1% 2 51 5
ZOLEDRONIC ACID 96 0.3% 3 28 7
OXALIPLATIN 94 0.2% 1 38 5
CARBOPLATIN 73 0.1% 6 36 4
GEMCITABINE 72 0.2% 0 29 3
VINCRISTINE 69 0.1% 6 59 36
DABRAFENIB 68 0.4% 7 22 2
DOXORUBICIN 66 0.1% 7 56 33
CYTARABINE 65 0.2% 5 18 9
PERTUZUMAB 65 0.3% 1 22 3
ACETAMINOPHEN 62 0.1% 0 43 36
IBUPROFEN 61 0.1% 1 52 38
DARATUMUMAB 58 0.2% 0 11 1
ALBUMIN HUMAN 47 1.9% 0 8 2
BEVACIZUMAB 47 0.1% 5 16 1
ETOPOSIDE 44 0.1% 1 39 31
METHOTREXATE 44 0.0% 3 23 3

View all 231 drugs →

Top 3 Drugs Associated With Hyperpyrexia

146 reports
139 reports
133 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)