Does LAMOTRIGINE Cause Pancytopenia? 189 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 189 reports of Pancytopenia have been filed in association with LAMOTRIGINE (Lamotrigine ER). This represents 0.4% of all adverse event reports for LAMOTRIGINE.
189
Reports of Pancytopenia with LAMOTRIGINE
0.4%
of all LAMOTRIGINE reports
24
Deaths
128
Hospitalizations
How Dangerous Is Pancytopenia From LAMOTRIGINE?
Of the 189 reports, 24 (12.7%) resulted in death, 128 (67.7%) required hospitalization, and 48 (25.4%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMOTRIGINE. However, 189 reports have been filed with the FAERS database.
What Other Side Effects Does LAMOTRIGINE Cause?
Drug ineffective (5,175)
Seizure (3,459)
Toxicity to various agents (3,256)
Rash (3,249)
Foetal exposure during pregnancy (2,985)
Off label use (2,625)
Completed suicide (2,433)
Drug reaction with eosinophilia and systemic symptoms (2,235)
Dizziness (2,170)
Pyrexia (1,967)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which LAMOTRIGINE Alternatives Have Lower Pancytopenia Risk?
LAMOTRIGINE vs LANADELUMAB
LAMOTRIGINE vs LANADELUMAB-FLYO
LAMOTRIGINE vs LANREOTIDE
LAMOTRIGINE vs LANSOPRAZOLE
LAMOTRIGINE vs LANTHANUM