Does LAMOTRIGINE Cause Pemphigus? 660 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 660 reports of Pemphigus have been filed in association with LAMOTRIGINE (Lamotrigine ER). This represents 1.4% of all adverse event reports for LAMOTRIGINE.
660
Reports of Pemphigus with LAMOTRIGINE
1.4%
of all LAMOTRIGINE reports
653
Deaths
572
Hospitalizations
How Dangerous Is Pemphigus From LAMOTRIGINE?
Of the 660 reports, 653 (98.9%) resulted in death, 572 (86.7%) required hospitalization, and 580 (87.9%) were considered life-threatening.
Is Pemphigus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMOTRIGINE. However, 660 reports have been filed with the FAERS database.
What Other Side Effects Does LAMOTRIGINE Cause?
Drug ineffective (5,175)
Seizure (3,459)
Toxicity to various agents (3,256)
Rash (3,249)
Foetal exposure during pregnancy (2,985)
Off label use (2,625)
Completed suicide (2,433)
Drug reaction with eosinophilia and systemic symptoms (2,235)
Dizziness (2,170)
Pyrexia (1,967)
What Other Drugs Cause Pemphigus?
RITUXIMAB (8,574)
ABATACEPT (8,441)
METHOTREXATE (8,414)
PREDNISONE (8,260)
LEFLUNOMIDE (8,252)
TOCILIZUMAB (8,210)
FOLIC ACID (8,128)
ADALIMUMAB (8,079)
CETIRIZINE (8,063)
HYDROXYCHLOROQUINE (8,051)
Which LAMOTRIGINE Alternatives Have Lower Pemphigus Risk?
LAMOTRIGINE vs LANADELUMAB
LAMOTRIGINE vs LANADELUMAB-FLYO
LAMOTRIGINE vs LANREOTIDE
LAMOTRIGINE vs LANSOPRAZOLE
LAMOTRIGINE vs LANTHANUM