Does LAPATINIB Cause Neutropenia? 160 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 160 reports of Neutropenia have been filed in association with LAPATINIB. This represents 8.1% of all adverse event reports for LAPATINIB.
160
Reports of Neutropenia with LAPATINIB
8.1%
of all LAPATINIB reports
11
Deaths
27
Hospitalizations
How Dangerous Is Neutropenia From LAPATINIB?
Of the 160 reports, 11 (6.9%) resulted in death, 27 (16.9%) required hospitalization, and 12 (7.5%) were considered life-threatening.
Is Neutropenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAPATINIB. However, 160 reports have been filed with the FAERS database.
What Other Side Effects Does LAPATINIB Cause?
Diarrhoea (382)
Disease progression (227)
Palmar-plantar erythrodysaesthesia syndrome (182)
Malignant neoplasm progression (173)
Nausea (161)
Metastases to central nervous system (160)
Vomiting (155)
Asthenia (148)
Fatigue (139)
Off label use (118)
What Other Drugs Cause Neutropenia?
CLOZAPINE (18,981)
CYCLOPHOSPHAMIDE (7,352)
LENALIDOMIDE (6,909)
RITUXIMAB (6,607)
PALBOCICLIB (6,423)
DEXAMETHASONE (6,050)
DOXORUBICIN (5,891)
CARBOPLATIN (5,314)
VINCRISTINE (4,982)
PACLITAXEL (4,553)
Which LAPATINIB Alternatives Have Lower Neutropenia Risk?
LAPATINIB vs LAPATINIB DITOSYLATE
LAPATINIB vs LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN
LAPATINIB vs LARONIDASE
LAPATINIB vs LAROTRECTINIB
LAPATINIB vs LASILIX