Does LAPATINIB Cause Off label use? 118 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 118 reports of Off label use have been filed in association with LAPATINIB. This represents 6.0% of all adverse event reports for LAPATINIB.
118
Reports of Off label use with LAPATINIB
6.0%
of all LAPATINIB reports
12
Deaths
42
Hospitalizations
How Dangerous Is Off label use From LAPATINIB?
Of the 118 reports, 12 (10.2%) resulted in death, 42 (35.6%) required hospitalization.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAPATINIB. However, 118 reports have been filed with the FAERS database.
What Other Side Effects Does LAPATINIB Cause?
Diarrhoea (382)
Disease progression (227)
Palmar-plantar erythrodysaesthesia syndrome (182)
Malignant neoplasm progression (173)
Nausea (161)
Metastases to central nervous system (160)
Neutropenia (160)
Vomiting (155)
Asthenia (148)
Fatigue (139)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which LAPATINIB Alternatives Have Lower Off label use Risk?
LAPATINIB vs LAPATINIB DITOSYLATE
LAPATINIB vs LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN
LAPATINIB vs LARONIDASE
LAPATINIB vs LAROTRECTINIB
LAPATINIB vs LASILIX