Does LARONIDASE Cause Cardiomegaly? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Cardiomegaly have been filed in association with LARONIDASE (ALDURAZYME). This represents 0.4% of all adverse event reports for LARONIDASE.
12
Reports of Cardiomegaly with LARONIDASE
0.4%
of all LARONIDASE reports
3
Deaths
7
Hospitalizations
How Dangerous Is Cardiomegaly From LARONIDASE?
Of the 12 reports, 3 (25.0%) resulted in death, 7 (58.3%) required hospitalization, and 1 (8.3%) were considered life-threatening.
Is Cardiomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LARONIDASE. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does LARONIDASE Cause?
Pyrexia (423)
Malaise (169)
Pneumonia (162)
Dyspnoea (157)
Vomiting (157)
Cough (154)
Fatigue (137)
Influenza (108)
Pain (107)
Inappropriate schedule of product administration (106)
What Other Drugs Cause Cardiomegaly?
SACUBITRIL\VALSARTAN (365)
ADALIMUMAB (301)
ONDANSETRON (198)
OXYCODONE (164)
AMLODIPINE (161)
CARVEDILOL (151)
MACITENTAN (141)
ACETAMINOPHEN (133)
TREPROSTINIL (129)
FUROSEMIDE (122)
Which LARONIDASE Alternatives Have Lower Cardiomegaly Risk?
LARONIDASE vs LAROTRECTINIB
LARONIDASE vs LASILIX
LARONIDASE vs LASIX
LARONIDASE vs LASMIDITAN
LARONIDASE vs LATANOPROST