Cardiomegaly: Which Medications Cause It? (6,351 Reports Across 483 Drugs)
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Cardiomegaly has been reported as an adverse event with 483 different drugs in the FDA's FAERS database, with 6,351 total reports. 1,513 of these reports resulted in death.The drugs most commonly associated with Cardiomegaly are SACUBITRIL\VALSARTAN, ADALIMUMAB, and ONDANSETRON.
6,351
Total Reports
483
Drugs Involved
1,513
Deaths
3,473
Hospitalizations
57.1 yrs
Average Patient Age
56.3% / 43.8%
Female / Male
Which Drugs Cause Cardiomegaly Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| SACUBITRIL\VALSARTAN | 365 | 0.3% | 69 | 171 | 20 |
| ADALIMUMAB | 301 | 0.1% | 37 | 179 | 14 |
| ONDANSETRON | 198 | 0.9% | 32 | 66 | 10 |
| OXYCODONE | 164 | 0.1% | 147 | 36 | 11 |
| AMLODIPINE | 161 | 0.3% | 38 | 120 | 6 |
| CARVEDILOL | 151 | 1.1% | 19 | 104 | 3 |
| MACITENTAN | 141 | 0.3% | 38 | 117 | 8 |
| ACETAMINOPHEN | 133 | 0.1% | 60 | 70 | 32 |
| TREPROSTINIL | 129 | 0.1% | 23 | 87 | 14 |
| FUROSEMIDE | 122 | 0.2% | 17 | 67 | 11 |
| ASPIRIN | 116 | 0.1% | 10 | 85 | 17 |
| BISOPROLOL | 110 | 0.4% | 42 | 90 | 25 |
| CLOZAPINE | 110 | 0.1% | 61 | 38 | 15 |
| VALSARTAN | 108 | 0.5% | 16 | 56 | 4 |
| PANTOPRAZOLE | 104 | 0.1% | 30 | 92 | 23 |
| METHOTREXATE | 98 | 0.0% | 11 | 53 | 19 |
| VENLAFAXINE | 96 | 0.2% | 52 | 54 | 27 |
| AMBRISENTAN | 93 | 0.1% | 10 | 59 | 4 |
| METFORMIN | 93 | 0.1% | 15 | 78 | 11 |
| ROSUVASTATIN | 93 | 0.3% | 11 | 50 | 12 |