Does CLOZAPINE Cause Cardiomegaly? 110 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 110 reports of Cardiomegaly have been filed in association with CLOZAPINE (CLOZAPINE). This represents 0.1% of all adverse event reports for CLOZAPINE.
110
Reports of Cardiomegaly with CLOZAPINE
0.1%
of all CLOZAPINE reports
61
Deaths
38
Hospitalizations
How Dangerous Is Cardiomegaly From CLOZAPINE?
Of the 110 reports, 61 (55.5%) resulted in death, 38 (34.5%) required hospitalization, and 15 (13.6%) were considered life-threatening.
Is Cardiomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLOZAPINE. However, 110 reports have been filed with the FAERS database.
What Other Side Effects Does CLOZAPINE Cause?
Neutropenia (18,981)
Hospitalisation (12,144)
Death (9,500)
Schizophrenia (3,991)
White blood cell count decreased (3,454)
Off label use (3,192)
Neutrophil count increased (3,125)
Drug ineffective (3,105)
Neutrophilia (3,105)
White blood cell count increased (2,988)
What Other Drugs Cause Cardiomegaly?
SACUBITRIL\VALSARTAN (365)
ADALIMUMAB (301)
ONDANSETRON (198)
OXYCODONE (164)
AMLODIPINE (161)
CARVEDILOL (151)
MACITENTAN (141)
ACETAMINOPHEN (133)
TREPROSTINIL (129)
FUROSEMIDE (122)
Which CLOZAPINE Alternatives Have Lower Cardiomegaly Risk?
CLOZAPINE vs CLOZARIL
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTEIN C\PROTEIN S HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN\ISOPROPYL ALCOHOL