Does CLOZAPINE Cause Off label use? 3,192 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 3,192 reports of Off label use have been filed in association with CLOZAPINE (CLOZAPINE). This represents 3.3% of all adverse event reports for CLOZAPINE.
3,192
Reports of Off label use with CLOZAPINE
3.3%
of all CLOZAPINE reports
403
Deaths
1,674
Hospitalizations
How Dangerous Is Off label use From CLOZAPINE?
Of the 3,192 reports, 403 (12.6%) resulted in death, 1,674 (52.4%) required hospitalization, and 186 (5.8%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLOZAPINE. However, 3,192 reports have been filed with the FAERS database.
What Other Side Effects Does CLOZAPINE Cause?
Neutropenia (18,981)
Hospitalisation (12,144)
Death (9,500)
Schizophrenia (3,991)
White blood cell count decreased (3,454)
Neutrophil count increased (3,125)
Drug ineffective (3,105)
Neutrophilia (3,105)
White blood cell count increased (2,988)
Neutrophil count decreased (2,523)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which CLOZAPINE Alternatives Have Lower Off label use Risk?
CLOZAPINE vs CLOZARIL
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTEIN C\PROTEIN S HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN\ISOPROPYL ALCOHOL