Does LETROZOLE Cause Pathological fracture? 87 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 87 reports of Pathological fracture have been filed in association with LETROZOLE (Letrozole). This represents 0.3% of all adverse event reports for LETROZOLE.
87
Reports of Pathological fracture with LETROZOLE
0.3%
of all LETROZOLE reports
5
Deaths
43
Hospitalizations
How Dangerous Is Pathological fracture From LETROZOLE?
Of the 87 reports, 5 (5.7%) resulted in death, 43 (49.4%) required hospitalization, and 2 (2.3%) were considered life-threatening.
Is Pathological fracture Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LETROZOLE. However, 87 reports have been filed with the FAERS database.
What Other Side Effects Does LETROZOLE Cause?
Neutropenia (3,683)
Fatigue (3,568)
Malignant neoplasm progression (3,445)
Nausea (2,894)
Arthralgia (2,318)
Diarrhoea (2,282)
Metastases to bone (1,735)
Dyspnoea (1,621)
Asthenia (1,589)
Vomiting (1,560)
What Other Drugs Cause Pathological fracture?
DENOSUMAB (634)
LENALIDOMIDE (260)
DEXAMETHASONE (201)
ALENDRONATE (200)
ZOLEDRONIC ACID (185)
RISEDRONATE (110)
ADALIMUMAB (93)
RITUXIMAB (87)
CYCLOPHOSPHAMIDE (85)
POMALIDOMIDE (85)
Which LETROZOLE Alternatives Have Lower Pathological fracture Risk?
LETROZOLE vs LETROZOLE\RIBOCICLIB
LETROZOLE vs LEUCOVORIN
LETROZOLE vs LEUCOVORIN\LEUCOVORIN
LETROZOLE vs LEUPROLIDE
LETROZOLE vs LEVALBUTEROL