LEUCOVORIN for Prophylaxis: Side Effects & Safety Data
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There are 253 adverse event reports in the FDA FAERS database where LEUCOVORIN was used for Prophylaxis.
Most Reported Side Effects for LEUCOVORIN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 2,594 | 10.4% | 338 | 1,219 |
| Neutropenia | 2,291 | 9.2% | 282 | 686 |
| Nausea | 1,977 | 7.9% | 215 | 934 |
| Neuropathy peripheral | 1,557 | 6.2% | 121 | 211 |
| Disease progression | 1,456 | 5.8% | 397 | 187 |
| Fatigue | 1,443 | 5.8% | 180 | 595 |
| Vomiting | 1,441 | 5.8% | 203 | 842 |
| Off label use | 1,390 | 5.6% | 267 | 525 |
| Thrombocytopenia | 1,181 | 4.7% | 154 | 336 |
| Pyrexia | 1,148 | 4.6% | 111 | 916 |
| Febrile neutropenia | 1,095 | 4.4% | 161 | 666 |
| Drug ineffective | 1,039 | 4.2% | 205 | 274 |
| Anaemia | 1,027 | 4.1% | 150 | 466 |
| Asthenia | 879 | 3.5% | 131 | 463 |
| Death | 844 | 3.4% | 844 | 92 |
Other Indications for LEUCOVORIN
Colorectal cancer metastatic (4,624)
Product used for unknown indication (2,770)
Colorectal cancer (1,478)
Colon cancer (1,364)
Adenocarcinoma of colon (926)
Acute lymphocytic leukaemia (759)
Pancreatic carcinoma (700)
Rectal cancer (660)
Metastases to liver (655)
Pancreatic carcinoma metastatic (637)
Other Drugs Used for Prophylaxis
PEGFILGRASTIM (7,424)
HUMAN C1-ESTERASE INHIBITOR (5,950)
DENOSUMAB (4,541)
SULFAMETHOXAZOLE\TRIMETHOPRIM (3,197)
ASPIRIN (2,083)
VALACYCLOVIR (1,574)
PANTOPRAZOLE (1,502)
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN (1,444)
CLOPIDOGREL BISULFATE (1,296)
ENOXAPARIN (1,278)