LINACLOTIDE for Constipation: Side Effects & Safety Data
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There are 5,348 adverse event reports in the FDA FAERS database where LINACLOTIDE was used for Constipation.
Most Reported Side Effects for LINACLOTIDE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 3,638 | 27.3% | 8 | 136 |
| Drug ineffective | 3,560 | 26.7% | 3 | 50 |
| Off label use | 2,634 | 19.8% | 16 | 81 |
| Constipation | 1,123 | 8.4% | 2 | 106 |
| Abdominal distension | 861 | 6.5% | 2 | 27 |
| Abdominal pain | 674 | 5.1% | 3 | 53 |
| Abdominal pain upper | 571 | 4.3% | 1 | 33 |
| Flatulence | 554 | 4.2% | 0 | 13 |
| Inappropriate schedule of product administration | 547 | 4.1% | 0 | 11 |
| Intentional product misuse | 462 | 3.5% | 0 | 13 |
| Nausea | 439 | 3.3% | 3 | 54 |
| Inappropriate schedule of drug administration | 352 | 2.6% | 0 | 9 |
| Product storage error | 350 | 2.6% | 0 | 2 |
| Incorrect dose administered | 340 | 2.6% | 3 | 25 |
| Dizziness | 303 | 2.3% | 0 | 30 |
Other Indications for LINACLOTIDE
Product used for unknown indication (3,720)
Irritable bowel syndrome (2,493)
Gastrointestinal disorder (57)
Gastrointestinal motility disorder (56)
Bowel movement irregularity (51)
Abdominal distension (39)
Impaired gastric emptying (39)
Diarrhoea (37)
Diverticulitis (37)
Intestinal obstruction (34)
Other Drugs Used for Constipation
POLYETHYLENE GLYCOL 3350 (9,960)
NALOXEGOL OXALATE (1,418)
LACTULOSE (1,115)
BISACODYL (1,013)
POLYETHYLENE GLYCOL 3350\POTASSIUM\SODIUM BICARBONATE\SODIUM (709)
POLYETHYLENE GLYCOLS (667)
MAGNESIUM (648)
MAGNESIUM HYDROXIDE (635)
LUBIPROSTONE (563)
PLECANATIDE (504)