Does LOPERAMIDE Cause Cardiomegaly? 36 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 36 reports of Cardiomegaly have been filed in association with LOPERAMIDE (Anti-diarrheal). This represents 0.2% of all adverse event reports for LOPERAMIDE.
36
Reports of Cardiomegaly with LOPERAMIDE
0.2%
of all LOPERAMIDE reports
34
Deaths
3
Hospitalizations
How Dangerous Is Cardiomegaly From LOPERAMIDE?
Of the 36 reports, 34 (94.4%) resulted in death, 3 (8.3%) required hospitalization, and 2 (5.6%) were considered life-threatening.
Is Cardiomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LOPERAMIDE. However, 36 reports have been filed with the FAERS database.
What Other Side Effects Does LOPERAMIDE Cause?
Drug ineffective (3,207)
Diarrhoea (1,909)
Constipation (1,614)
Off label use (1,378)
Incorrect dose administered (1,178)
Drug abuse (1,088)
Nausea (997)
Intentional product use issue (871)
Overdose (857)
Toxicity to various agents (753)
What Other Drugs Cause Cardiomegaly?
SACUBITRIL\VALSARTAN (365)
ADALIMUMAB (301)
ONDANSETRON (198)
OXYCODONE (164)
AMLODIPINE (161)
CARVEDILOL (151)
MACITENTAN (141)
ACETAMINOPHEN (133)
TREPROSTINIL (129)
FUROSEMIDE (122)
Which LOPERAMIDE Alternatives Have Lower Cardiomegaly Risk?
LOPERAMIDE vs LOPINAVIR
LOPERAMIDE vs LOPINAVIR\RITONAVIR
LOPERAMIDE vs LOPRAZOLAM
LOPERAMIDE vs LORATADINE
LOPERAMIDE vs LORATADINE\PSEUDOEPHEDRINE