Does LORLATINIB Cause Anal incontinence? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Anal incontinence have been filed in association with LORLATINIB (Lorbrena). This represents 0.2% of all adverse event reports for LORLATINIB.
10
Reports of Anal incontinence with LORLATINIB
0.2%
of all LORLATINIB reports
2
Deaths
5
Hospitalizations
How Dangerous Is Anal incontinence From LORLATINIB?
Of the 10 reports, 2 (20.0%) resulted in death, 5 (50.0%) required hospitalization, and 1 (10.0%) were considered life-threatening.
Is Anal incontinence Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LORLATINIB. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does LORLATINIB Cause?
Death (1,050)
Neoplasm progression (633)
Off label use (394)
Weight increased (306)
Hallucination (290)
Blood cholesterol increased (281)
Dyspnoea (223)
Oedema peripheral (198)
Oedema (195)
Fatigue (188)
What Other Drugs Cause Anal incontinence?
ADALIMUMAB (480)
VEDOLIZUMAB (457)
POLYETHYLENE GLYCOL 3350 (185)
INFLIXIMAB (172)
DIMETHYL (157)
METHOTREXATE (157)
LINACLOTIDE (135)
METFORMIN (127)
FINGOLIMOD (126)
ORLISTAT (125)
Which LORLATINIB Alternatives Have Lower Anal incontinence Risk?
LORLATINIB vs LORMETAZEPAM
LORLATINIB vs LORNOXICAM
LORLATINIB vs LOSARTAN
LORLATINIB vs LOSARTAN\LOSARTAN
LORLATINIB vs LOTEPREDNOL ETABONATE