Does METHOTREXATE Cause Anal incontinence? 157 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 157 reports of Anal incontinence have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
157
Reports of Anal incontinence with METHOTREXATE
0.1%
of all METHOTREXATE reports
5
Deaths
73
Hospitalizations
How Dangerous Is Anal incontinence From METHOTREXATE?
Of the 157 reports, 5 (3.2%) resulted in death, 73 (46.5%) required hospitalization, and 19 (12.1%) were considered life-threatening.
Is Anal incontinence Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 157 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Anal incontinence?
ADALIMUMAB (480)
VEDOLIZUMAB (457)
POLYETHYLENE GLYCOL 3350 (185)
INFLIXIMAB (172)
DIMETHYL (157)
LINACLOTIDE (135)
METFORMIN (127)
FINGOLIMOD (126)
ORLISTAT (125)
CARBIDOPA\LEVODOPA (124)
Which METHOTREXATE Alternatives Have Lower Anal incontinence Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA