Does LORLATINIB Cause Cardiac failure? 57 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 57 reports of Cardiac failure have been filed in association with LORLATINIB (Lorbrena). This represents 1.0% of all adverse event reports for LORLATINIB.
57
Reports of Cardiac failure with LORLATINIB
1.0%
of all LORLATINIB reports
10
Deaths
22
Hospitalizations
How Dangerous Is Cardiac failure From LORLATINIB?
Of the 57 reports, 10 (17.5%) resulted in death, 22 (38.6%) required hospitalization, and 3 (5.3%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
Yes, Cardiac failure is listed as a known adverse reaction in the official FDA drug label for LORLATINIB.
What Other Side Effects Does LORLATINIB Cause?
Death (1,050)
Neoplasm progression (633)
Off label use (394)
Weight increased (306)
Hallucination (290)
Blood cholesterol increased (281)
Dyspnoea (223)
Oedema peripheral (198)
Oedema (195)
Fatigue (188)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which LORLATINIB Alternatives Have Lower Cardiac failure Risk?
LORLATINIB vs LORMETAZEPAM
LORLATINIB vs LORNOXICAM
LORLATINIB vs LOSARTAN
LORLATINIB vs LOSARTAN\LOSARTAN
LORLATINIB vs LOTEPREDNOL ETABONATE