Does LORLATINIB Cause Hypercholesterolaemia? 157 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 157 reports of Hypercholesterolaemia have been filed in association with LORLATINIB (Lorbrena). This represents 2.9% of all adverse event reports for LORLATINIB.
157
Reports of Hypercholesterolaemia with LORLATINIB
2.9%
of all LORLATINIB reports
19
Deaths
43
Hospitalizations
How Dangerous Is Hypercholesterolaemia From LORLATINIB?
Of the 157 reports, 19 (12.1%) resulted in death, 43 (27.4%) required hospitalization, and 6 (3.8%) were considered life-threatening.
Is Hypercholesterolaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LORLATINIB. However, 157 reports have been filed with the FAERS database.
What Other Side Effects Does LORLATINIB Cause?
Death (1,050)
Neoplasm progression (633)
Off label use (394)
Weight increased (306)
Hallucination (290)
Blood cholesterol increased (281)
Dyspnoea (223)
Oedema peripheral (198)
Oedema (195)
Fatigue (188)
What Other Drugs Cause Hypercholesterolaemia?
ALENDRONATE (1,607)
METHOTREXATE (1,547)
TOCILIZUMAB (1,483)
ADALIMUMAB (1,479)
ABATACEPT (1,410)
RITUXIMAB (1,389)
PREDNISONE (1,377)
INFLIXIMAB (1,338)
DICLOFENAC (1,331)
LEFLUNOMIDE (1,322)
Which LORLATINIB Alternatives Have Lower Hypercholesterolaemia Risk?
LORLATINIB vs LORMETAZEPAM
LORLATINIB vs LORNOXICAM
LORLATINIB vs LOSARTAN
LORLATINIB vs LOSARTAN\LOSARTAN
LORLATINIB vs LOTEPREDNOL ETABONATE