Does METHOTREXATE Cause Hypercholesterolaemia? 1,547 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,547 reports of Hypercholesterolaemia have been filed in association with METHOTREXATE (Methotrexate). This represents 0.6% of all adverse event reports for METHOTREXATE.
1,547
Reports of Hypercholesterolaemia with METHOTREXATE
0.6%
of all METHOTREXATE reports
1,210
Deaths
990
Hospitalizations
How Dangerous Is Hypercholesterolaemia From METHOTREXATE?
Of the 1,547 reports, 1,210 (78.2%) resulted in death, 990 (64.0%) required hospitalization, and 965 (62.4%) were considered life-threatening.
Is Hypercholesterolaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 1,547 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Hypercholesterolaemia?
ALENDRONATE (1,607)
TOCILIZUMAB (1,483)
ADALIMUMAB (1,479)
ABATACEPT (1,410)
RITUXIMAB (1,389)
PREDNISONE (1,377)
INFLIXIMAB (1,338)
DICLOFENAC (1,331)
LEFLUNOMIDE (1,322)
CERTOLIZUMAB PEGOL (1,321)
Which METHOTREXATE Alternatives Have Lower Hypercholesterolaemia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA