MACITENTAN for Scleroderma: Side Effects & Safety Data
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There are 21 adverse event reports in the FDA FAERS database where MACITENTAN was used for Scleroderma.
Most Reported Side Effects for MACITENTAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Dyspnoea | 8,315 | 18.4% | 1,685 | 5,903 |
| Death | 5,864 | 12.9% | 5,789 | 2,120 |
| Headache | 4,856 | 10.7% | 575 | 2,694 |
| Diarrhoea | 3,669 | 8.1% | 574 | 2,268 |
| Pneumonia | 3,531 | 7.8% | 810 | 3,162 |
| Nausea | 3,463 | 7.6% | 456 | 2,116 |
| Hospitalisation | 3,414 | 7.5% | 500 | 3,372 |
| Fatigue | 3,172 | 7.0% | 485 | 1,899 |
| Fluid retention | 2,861 | 6.3% | 575 | 2,150 |
| Dizziness | 2,704 | 6.0% | 337 | 1,673 |
| Malaise | 2,521 | 5.6% | 431 | 1,590 |
| Pulmonary arterial hypertension | 2,390 | 5.3% | 1,204 | 1,695 |
| Hypotension | 2,318 | 5.1% | 519 | 1,691 |
| Cough | 2,294 | 5.1% | 314 | 1,404 |
| Condition aggravated | 2,198 | 4.9% | 638 | 1,538 |
Other Indications for MACITENTAN
Pulmonary arterial hypertension (29,246)
Product used for unknown indication (9,498)
Pulmonary hypertension (5,228)
Cor pulmonale chronic (254)
Portopulmonary hypertension (153)
Connective tissue disorder (107)
Systemic scleroderma (74)
Pulmonary embolism (68)
Heart disease congenital (56)
Heritable pulmonary arterial hypertension (43)
Other Drugs Used for Scleroderma
AMBRISENTAN (1,547)
RITUXIMAB (252)
METHOTREXATE (145)
MYCOPHENOLATE MOFETIL (144)
LETAIRIS (120)
TOCILIZUMAB (117)
PREDNISONE (83)
SILDENAFIL (78)
BOSENTAN (52)
HYDROXYCHLOROQUINE (49)