MACITENTAN for Systemic scleroderma: Side Effects & Safety Data
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There are 74 adverse event reports in the FDA FAERS database where MACITENTAN was used for Systemic scleroderma.
Most Reported Side Effects for MACITENTAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Dyspnoea | 8,315 | 18.4% | 1,685 | 5,903 |
| Death | 5,864 | 12.9% | 5,789 | 2,120 |
| Headache | 4,856 | 10.7% | 575 | 2,694 |
| Diarrhoea | 3,669 | 8.1% | 574 | 2,268 |
| Pneumonia | 3,531 | 7.8% | 810 | 3,162 |
| Nausea | 3,463 | 7.6% | 456 | 2,116 |
| Hospitalisation | 3,414 | 7.5% | 500 | 3,372 |
| Fatigue | 3,172 | 7.0% | 485 | 1,899 |
| Fluid retention | 2,861 | 6.3% | 575 | 2,150 |
| Dizziness | 2,704 | 6.0% | 337 | 1,673 |
| Malaise | 2,521 | 5.6% | 431 | 1,590 |
| Pulmonary arterial hypertension | 2,390 | 5.3% | 1,204 | 1,695 |
| Hypotension | 2,318 | 5.1% | 519 | 1,691 |
| Cough | 2,294 | 5.1% | 314 | 1,404 |
| Condition aggravated | 2,198 | 4.9% | 638 | 1,538 |
Other Indications for MACITENTAN
Pulmonary arterial hypertension (29,246)
Product used for unknown indication (9,498)
Pulmonary hypertension (5,228)
Cor pulmonale chronic (254)
Portopulmonary hypertension (153)
Connective tissue disorder (107)
Pulmonary embolism (68)
Heart disease congenital (56)
Heritable pulmonary arterial hypertension (43)
Right-to-left cardiac shunt (32)
Other Drugs Used for Systemic scleroderma
RITUXIMAB (554)
MYCOPHENOLATE MOFETIL (474)
TOCILIZUMAB (332)
METHOTREXATE (307)
NINTEDANIB (204)
PREDNISOLONE (156)
CYCLOPHOSPHAMIDE (142)
PREDNISONE (128)
BOSENTAN (120)
IMATINIB (118)