Does MACITENTAN Cause Hypervolaemia? 202 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 202 reports of Hypervolaemia have been filed in association with MACITENTAN (OPSYNVI). This represents 0.5% of all adverse event reports for MACITENTAN.
202
Reports of Hypervolaemia with MACITENTAN
0.5%
of all MACITENTAN reports
26
Deaths
158
Hospitalizations
How Dangerous Is Hypervolaemia From MACITENTAN?
Of the 202 reports, 26 (12.9%) resulted in death, 158 (78.2%) required hospitalization, and 3 (1.5%) were considered life-threatening.
Is Hypervolaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MACITENTAN. However, 202 reports have been filed with the FAERS database.
What Other Side Effects Does MACITENTAN Cause?
Dyspnoea (8,315)
Death (5,864)
Headache (4,856)
Diarrhoea (3,669)
Pneumonia (3,531)
Nausea (3,463)
Hospitalisation (3,414)
Fatigue (3,172)
Fluid retention (2,861)
Dizziness (2,704)
What Other Drugs Cause Hypervolaemia?
TREPROSTINIL (580)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (428)
AMBRISENTAN (205)
FUROSEMIDE (139)
AMLODIPINE (122)
CYCLOPHOSPHAMIDE (118)
SACUBITRIL\VALSARTAN (115)
TACROLIMUS (100)
PREDNISONE (98)
MYCOPHENOLATE MOFETIL (89)
Which MACITENTAN Alternatives Have Lower Hypervolaemia Risk?
MACITENTAN vs MACITENTAN\TADALAFIL
MACITENTAN vs MAGNESIUM
MACITENTAN vs MAGNESIUM ASPARTATE
MACITENTAN vs MAGNESIUM ASPARTATE\POTASSIUM ASPARTATE
MACITENTAN vs MAGNESIUM HYDROXIDE