Does MACITENTAN Cause Portal hypertension? 49 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 49 reports of Portal hypertension have been filed in association with MACITENTAN (OPSYNVI). This represents 0.1% of all adverse event reports for MACITENTAN.
49
Reports of Portal hypertension with MACITENTAN
0.1%
of all MACITENTAN reports
15
Deaths
35
Hospitalizations
How Dangerous Is Portal hypertension From MACITENTAN?
Of the 49 reports, 15 (30.6%) resulted in death, 35 (71.4%) required hospitalization, and 8 (16.3%) were considered life-threatening.
Is Portal hypertension Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MACITENTAN. However, 49 reports have been filed with the FAERS database.
What Other Side Effects Does MACITENTAN Cause?
Dyspnoea (8,315)
Death (5,864)
Headache (4,856)
Diarrhoea (3,669)
Pneumonia (3,531)
Nausea (3,463)
Hospitalisation (3,414)
Fatigue (3,172)
Fluid retention (2,861)
Dizziness (2,704)
What Other Drugs Cause Portal hypertension?
OXALIPLATIN (289)
BEVACIZUMAB (141)
FLUOROURACIL (108)
CYCLOPHOSPHAMIDE (98)
METHOTREXATE (98)
CAPECITABINE (86)
LEUCOVORIN (85)
AZATHIOPRINE (75)
TACROLIMUS (73)
ADO-TRASTUZUMAB EMTANSINE (67)
Which MACITENTAN Alternatives Have Lower Portal hypertension Risk?
MACITENTAN vs MACITENTAN\TADALAFIL
MACITENTAN vs MAGNESIUM
MACITENTAN vs MAGNESIUM ASPARTATE
MACITENTAN vs MAGNESIUM ASPARTATE\POTASSIUM ASPARTATE
MACITENTAN vs MAGNESIUM HYDROXIDE