Portal hypertension: Which Medications Cause It? (2,040 Reports Across 214 Drugs)
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Portal hypertension has been reported as an adverse event with 214 different drugs in the FDA's FAERS database, with 2,040 total reports. 313 of these reports resulted in death.The drugs most commonly associated with Portal hypertension are OXALIPLATIN, BEVACIZUMAB, and FLUOROURACIL.
2,040
Total Reports
214
Drugs Involved
313
Deaths
978
Hospitalizations
54.0 yrs
Average Patient Age
45.5% / 54.5%
Female / Male
Which Drugs Cause Portal hypertension Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| OXALIPLATIN | 289 | 0.5% | 20 | 140 | 21 |
| BEVACIZUMAB | 141 | 0.2% | 26 | 60 | 5 |
| FLUOROURACIL | 108 | 0.2% | 12 | 61 | 4 |
| CYCLOPHOSPHAMIDE | 98 | 0.1% | 10 | 24 | 1 |
| METHOTREXATE | 98 | 0.0% | 7 | 36 | 3 |
| CAPECITABINE | 86 | 0.1% | 22 | 22 | 4 |
| LEUCOVORIN | 85 | 0.3% | 9 | 44 | 3 |
| AZATHIOPRINE | 75 | 0.2% | 3 | 19 | 3 |
| TACROLIMUS | 73 | 0.1% | 17 | 34 | 1 |
| ADO-TRASTUZUMAB EMTANSINE | 67 | 0.8% | 3 | 20 | 2 |
| RUXOLITINIB | 66 | 0.1% | 26 | 30 | 2 |
| PACLITAXEL | 65 | 0.1% | 23 | 24 | 14 |
| OBETICHOLIC ACID | 62 | 0.9% | 7 | 20 | 0 |
| LAMIVUDINE | 61 | 0.4% | 11 | 37 | 1 |
| RIBAVIRIN | 57 | 0.1% | 7 | 29 | 6 |
| PREDNISONE | 56 | 0.0% | 4 | 30 | 3 |
| ATEZOLIZUMAB | 55 | 0.2% | 11 | 22 | 0 |
| DIDANOSINE | 53 | 2.6% | 1 | 17 | 2 |
| DOXORUBICIN | 53 | 0.1% | 7 | 25 | 0 |
| MACITENTAN | 49 | 0.1% | 15 | 35 | 8 |