Does PACLITAXEL Cause Portal hypertension? 65 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 65 reports of Portal hypertension have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.1% of all adverse event reports for PACLITAXEL.
65
Reports of Portal hypertension with PACLITAXEL
0.1%
of all PACLITAXEL reports
23
Deaths
24
Hospitalizations
How Dangerous Is Portal hypertension From PACLITAXEL?
Of the 65 reports, 23 (35.4%) resulted in death, 24 (36.9%) required hospitalization, and 14 (21.5%) were considered life-threatening.
Is Portal hypertension Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 65 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Portal hypertension?
OXALIPLATIN (289)
BEVACIZUMAB (141)
FLUOROURACIL (108)
CYCLOPHOSPHAMIDE (98)
METHOTREXATE (98)
CAPECITABINE (86)
LEUCOVORIN (85)
AZATHIOPRINE (75)
TACROLIMUS (73)
ADO-TRASTUZUMAB EMTANSINE (67)
Which PACLITAXEL Alternatives Have Lower Portal hypertension Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON