Does MANNITOL Cause Hyponatraemia? 153 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 153 reports of Hyponatraemia have been filed in association with MANNITOL (Osmitrol). This represents 7.7% of all adverse event reports for MANNITOL.
153
Reports of Hyponatraemia with MANNITOL
7.7%
of all MANNITOL reports
126
Deaths
103
Hospitalizations
How Dangerous Is Hyponatraemia From MANNITOL?
Of the 153 reports, 126 (82.4%) resulted in death, 103 (67.3%) required hospitalization, and 85 (55.6%) were considered life-threatening.
Is Hyponatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MANNITOL. However, 153 reports have been filed with the FAERS database.
What Other Side Effects Does MANNITOL Cause?
Drug ineffective (276)
Condition aggravated (205)
Nausea (167)
Off label use (159)
Vomiting (147)
Renal impairment (144)
Pruritus (140)
Sepsis (136)
Multiple organ dysfunction syndrome (131)
Abdominal pain (130)
What Other Drugs Cause Hyponatraemia?
FUROSEMIDE (3,127)
HYDROCHLOROTHIAZIDE (2,138)
OMEPRAZOLE (1,635)
LANSOPRAZOLE (1,416)
SERTRALINE (1,332)
RAMIPRIL (1,178)
SPIRONOLACTONE (1,166)
PANTOPRAZOLE (1,134)
INDAPAMIDE (976)
AMLODIPINE (879)
Which MANNITOL Alternatives Have Lower Hyponatraemia Risk?
MANNITOL vs MAPROTILINE
MANNITOL vs MARALIXIBAT
MANNITOL vs MARAVIROC
MANNITOL vs MARIBAVIR
MANNITOL vs MAVACAMTEN