Does MANNITOL Cause Hypophosphataemia? 85 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 85 reports of Hypophosphataemia have been filed in association with MANNITOL (Osmitrol). This represents 4.3% of all adverse event reports for MANNITOL.
85
Reports of Hypophosphataemia with MANNITOL
4.3%
of all MANNITOL reports
80
Deaths
75
Hospitalizations
How Dangerous Is Hypophosphataemia From MANNITOL?
Of the 85 reports, 80 (94.1%) resulted in death, 75 (88.2%) required hospitalization, and 70 (82.4%) were considered life-threatening.
Is Hypophosphataemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MANNITOL. However, 85 reports have been filed with the FAERS database.
What Other Side Effects Does MANNITOL Cause?
Drug ineffective (276)
Condition aggravated (205)
Nausea (167)
Off label use (159)
Hyponatraemia (153)
Vomiting (147)
Renal impairment (144)
Pruritus (140)
Sepsis (136)
Multiple organ dysfunction syndrome (131)
What Other Drugs Cause Hypophosphataemia?
FERRIC CARBOXYMALTOSE (1,046)
ADEFOVIR DIPIVOXIL (368)
DENOSUMAB (322)
ZOLEDRONIC ACID (235)
LAMIVUDINE (205)
CYCLOPHOSPHAMIDE (196)
TENOFOVIR DISOPROXIL (192)
DEXAMETHASONE (186)
ACETAMINOPHEN (169)
LANSOPRAZOLE (159)
Which MANNITOL Alternatives Have Lower Hypophosphataemia Risk?
MANNITOL vs MAPROTILINE
MANNITOL vs MARALIXIBAT
MANNITOL vs MARAVIROC
MANNITOL vs MARIBAVIR
MANNITOL vs MAVACAMTEN