Does MELPHALAN Cause Thrombocytopenia? 701 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 701 reports of Thrombocytopenia have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 4.4% of all adverse event reports for MELPHALAN.
701
Reports of Thrombocytopenia with MELPHALAN
4.4%
of all MELPHALAN reports
118
Deaths
253
Hospitalizations
How Dangerous Is Thrombocytopenia From MELPHALAN?
Of the 701 reports, 118 (16.8%) resulted in death, 253 (36.1%) required hospitalization, and 124 (17.7%) were considered life-threatening.
Is Thrombocytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 701 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Diarrhoea (698)
Pyrexia (667)
Pneumonia (650)
What Other Drugs Cause Thrombocytopenia?
DEXAMETHASONE (5,873)
RITUXIMAB (4,810)
CYCLOPHOSPHAMIDE (4,669)
LENALIDOMIDE (4,584)
CARBOPLATIN (4,483)
METHOTREXATE (3,865)
DOXORUBICIN (3,638)
ETOPOSIDE (3,085)
VINCRISTINE (2,940)
OXALIPLATIN (2,886)
Which MELPHALAN Alternatives Have Lower Thrombocytopenia Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL