Does MELPHALAN Cause Off label use? 2,002 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,002 reports of Off label use have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 12.5% of all adverse event reports for MELPHALAN.
2,002
Reports of Off label use with MELPHALAN
12.5%
of all MELPHALAN reports
437
Deaths
495
Hospitalizations
How Dangerous Is Off label use From MELPHALAN?
Of the 2,002 reports, 437 (21.8%) resulted in death, 495 (24.7%) required hospitalization, and 243 (12.1%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 2,002 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
Pneumonia (650)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which MELPHALAN Alternatives Have Lower Off label use Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL