Does MEPOLIZUMAB Cause Pemphigus? 615 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 615 reports of Pemphigus have been filed in association with MEPOLIZUMAB (Nucala). This represents 1.4% of all adverse event reports for MEPOLIZUMAB.
615
Reports of Pemphigus with MEPOLIZUMAB
1.4%
of all MEPOLIZUMAB reports
608
Deaths
530
Hospitalizations
How Dangerous Is Pemphigus From MEPOLIZUMAB?
Of the 615 reports, 608 (98.9%) resulted in death, 530 (86.2%) required hospitalization, and 535 (87.0%) were considered life-threatening.
Is Pemphigus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MEPOLIZUMAB. However, 615 reports have been filed with the FAERS database.
What Other Side Effects Does MEPOLIZUMAB Cause?
Asthma (11,033)
Dyspnoea (9,192)
Wheezing (6,093)
Product dose omission issue (5,873)
Cough (4,577)
Pneumonia (4,107)
Therapeutic product effect incomplete (4,106)
Drug ineffective (3,880)
Loss of personal independence in daily activities (3,566)
Fatigue (2,656)
What Other Drugs Cause Pemphigus?
RITUXIMAB (8,574)
ABATACEPT (8,441)
METHOTREXATE (8,414)
PREDNISONE (8,260)
LEFLUNOMIDE (8,252)
TOCILIZUMAB (8,210)
FOLIC ACID (8,128)
ADALIMUMAB (8,079)
CETIRIZINE (8,063)
HYDROXYCHLOROQUINE (8,051)
Which MEPOLIZUMAB Alternatives Have Lower Pemphigus Risk?
MEPOLIZUMAB vs MEPROBAMATE
MEPOLIZUMAB vs MERCAPTOPURINE
MEPOLIZUMAB vs MEROPENEM
MEPOLIZUMAB vs MEROPENEM ANHYDROUS
MEPOLIZUMAB vs MESALAMINE