Does METFORMIN Cause Gangrene? 218 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 218 reports of Gangrene have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.2% of all adverse event reports for METFORMIN.
218
Reports of Gangrene with METFORMIN
0.2%
of all METFORMIN reports
3
Deaths
203
Hospitalizations
How Dangerous Is Gangrene From METFORMIN?
Of the 218 reports, 3 (1.4%) resulted in death, 203 (93.1%) required hospitalization, and 134 (61.5%) were considered life-threatening.
Is Gangrene Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 218 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Gangrene?
CANAGLIFLOZIN (1,081)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (307)
RITUXIMAB (222)
PREDNISONE (201)
METHYLPREDNISOLONE (198)
AMLODIPINE (193)
LEVOTHYROXINE (189)
ESOMEPRAZOLE (185)
LISINOPRIL (184)
ACETAMINOPHEN (183)
Which METFORMIN Alternatives Have Lower Gangrene Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN