Does CANAGLIFLOZIN Cause Gangrene? 1,081 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,081 reports of Gangrene have been filed in association with CANAGLIFLOZIN (INVOKANA). This represents 4.4% of all adverse event reports for CANAGLIFLOZIN.
1,081
Reports of Gangrene with CANAGLIFLOZIN
4.4%
of all CANAGLIFLOZIN reports
14
Deaths
952
Hospitalizations
How Dangerous Is Gangrene From CANAGLIFLOZIN?
Of the 1,081 reports, 14 (1.3%) resulted in death, 952 (88.1%) required hospitalization, and 7 (0.6%) were considered life-threatening.
Is Gangrene Listed in the Official Label?
Yes, Gangrene is listed as a known adverse reaction in the official FDA drug label for CANAGLIFLOZIN.
What Other Side Effects Does CANAGLIFLOZIN Cause?
Diabetic ketoacidosis (3,413)
Toe amputation (2,193)
Osteomyelitis (2,146)
Acute kidney injury (1,853)
Fungal infection (1,385)
Weight decreased (1,014)
Cellulitis (1,007)
Urinary tract infection (920)
Diabetic foot infection (832)
Leg amputation (792)
What Other Drugs Cause Gangrene?
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (307)
RITUXIMAB (222)
METFORMIN (218)
PREDNISONE (201)
METHYLPREDNISOLONE (198)
AMLODIPINE (193)
LEVOTHYROXINE (189)
ESOMEPRAZOLE (185)
LISINOPRIL (184)
ACETAMINOPHEN (183)
Which CANAGLIFLOZIN Alternatives Have Lower Gangrene Risk?
CANAGLIFLOZIN vs CANAGLIFLOZIN\METFORMIN
CANAGLIFLOZIN vs CANAKINUMAB
CANAGLIFLOZIN vs CANDESARTAN
CANAGLIFLOZIN vs CANDESARTAN CILEXETIL
CANAGLIFLOZIN vs CANDESARTAN CILEXETIL\HYDROCHLOROTHIAZIDE