Does CANAGLIFLOZIN Cause Leg amputation? 792 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 792 reports of Leg amputation have been filed in association with CANAGLIFLOZIN (INVOKANA). This represents 3.2% of all adverse event reports for CANAGLIFLOZIN.
792
Reports of Leg amputation with CANAGLIFLOZIN
3.2%
of all CANAGLIFLOZIN reports
23
Deaths
668
Hospitalizations
How Dangerous Is Leg amputation From CANAGLIFLOZIN?
Of the 792 reports, 23 (2.9%) resulted in death, 668 (84.3%) required hospitalization, and 14 (1.8%) were considered life-threatening.
Is Leg amputation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CANAGLIFLOZIN. However, 792 reports have been filed with the FAERS database.
What Other Side Effects Does CANAGLIFLOZIN Cause?
Diabetic ketoacidosis (3,413)
Toe amputation (2,193)
Osteomyelitis (2,146)
Acute kidney injury (1,853)
Fungal infection (1,385)
Gangrene (1,081)
Weight decreased (1,014)
Cellulitis (1,007)
Urinary tract infection (920)
Diabetic foot infection (832)
What Other Drugs Cause Leg amputation?
INSULIN GLARGINE (157)
ADALIMUMAB (93)
METFORMIN (79)
EMPAGLIFLOZIN (67)
OXYCODONE (67)
CANAGLIFLOZIN\METFORMIN (62)
RIVAROXABAN (58)
INSULIN ASPART (49)
ETANERCEPT (43)
DARBEPOETIN ALFA (41)
Which CANAGLIFLOZIN Alternatives Have Lower Leg amputation Risk?
CANAGLIFLOZIN vs CANAGLIFLOZIN\METFORMIN
CANAGLIFLOZIN vs CANAKINUMAB
CANAGLIFLOZIN vs CANDESARTAN
CANAGLIFLOZIN vs CANDESARTAN CILEXETIL
CANAGLIFLOZIN vs CANDESARTAN CILEXETIL\HYDROCHLOROTHIAZIDE