Does CANAGLIFLOZIN\METFORMIN Cause Leg amputation? 62 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 62 reports of Leg amputation have been filed in association with CANAGLIFLOZIN\METFORMIN. This represents 4.0% of all adverse event reports for CANAGLIFLOZIN\METFORMIN.
62
Reports of Leg amputation with CANAGLIFLOZIN\METFORMIN
4.0%
of all CANAGLIFLOZIN\METFORMIN reports
1
Deaths
58
Hospitalizations
How Dangerous Is Leg amputation From CANAGLIFLOZIN\METFORMIN?
Of the 62 reports, 1 (1.6%) resulted in death, 58 (93.5%) required hospitalization, and 1 (1.6%) were considered life-threatening.
Is Leg amputation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CANAGLIFLOZIN\METFORMIN. However, 62 reports have been filed with the FAERS database.
What Other Side Effects Does CANAGLIFLOZIN\METFORMIN Cause?
Osteomyelitis (197)
Toe amputation (196)
Diabetic ketoacidosis (185)
Acute kidney injury (105)
Cellulitis (92)
Diabetic foot infection (85)
Gangrene (82)
Blood glucose increased (69)
Off label use (67)
Diabetic foot (65)
What Other Drugs Cause Leg amputation?
CANAGLIFLOZIN (792)
INSULIN GLARGINE (157)
ADALIMUMAB (93)
METFORMIN (79)
EMPAGLIFLOZIN (67)
OXYCODONE (67)
RIVAROXABAN (58)
INSULIN ASPART (49)
ETANERCEPT (43)
DARBEPOETIN ALFA (41)
Which CANAGLIFLOZIN\METFORMIN Alternatives Have Lower Leg amputation Risk?
CANAGLIFLOZIN\METFORMIN vs CANAKINUMAB
CANAGLIFLOZIN\METFORMIN vs CANDESARTAN
CANAGLIFLOZIN\METFORMIN vs CANDESARTAN CILEXETIL
CANAGLIFLOZIN\METFORMIN vs CANDESARTAN CILEXETIL\HYDROCHLOROTHIAZIDE
CANAGLIFLOZIN\METFORMIN vs CANGRELOR