Does METFORMIN Cause Leg amputation? 79 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 79 reports of Leg amputation have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.1% of all adverse event reports for METFORMIN.
79
Reports of Leg amputation with METFORMIN
0.1%
of all METFORMIN reports
12
Deaths
51
Hospitalizations
How Dangerous Is Leg amputation From METFORMIN?
Of the 79 reports, 12 (15.2%) resulted in death, 51 (64.6%) required hospitalization, and 6 (7.6%) were considered life-threatening.
Is Leg amputation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 79 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Leg amputation?
CANAGLIFLOZIN (792)
INSULIN GLARGINE (157)
ADALIMUMAB (93)
EMPAGLIFLOZIN (67)
OXYCODONE (67)
CANAGLIFLOZIN\METFORMIN (62)
RIVAROXABAN (58)
INSULIN ASPART (49)
ETANERCEPT (43)
DARBEPOETIN ALFA (41)
Which METFORMIN Alternatives Have Lower Leg amputation Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN