Does METFORMIN Cause Hyperlactacidaemia? 807 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 807 reports of Hyperlactacidaemia have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.9% of all adverse event reports for METFORMIN.
807
Reports of Hyperlactacidaemia with METFORMIN
0.9%
of all METFORMIN reports
111
Deaths
702
Hospitalizations
How Dangerous Is Hyperlactacidaemia From METFORMIN?
Of the 807 reports, 111 (13.8%) resulted in death, 702 (87.0%) required hospitalization, and 249 (30.9%) were considered life-threatening.
Is Hyperlactacidaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 807 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Hyperlactacidaemia?
AMLODIPINE (105)
LINEZOLID (105)
ACETAMINOPHEN (96)
QUETIAPINE (68)
IBUPROFEN (55)
METHYLPREDNISOLONE (54)
LANSOPRAZOLE (52)
NOREPINEPHRINE (52)
MIRTAZAPINE (46)
LORAZEPAM (44)
Which METFORMIN Alternatives Have Lower Hyperlactacidaemia Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN