Hyperlactacidaemia: Which Medications Cause It? (1,952 Reports Across 217 Drugs)
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Hyperlactacidaemia has been reported as an adverse event with 217 different drugs in the FDA's FAERS database, with 1,952 total reports. 387 of these reports resulted in death.The drugs most commonly associated with Hyperlactacidaemia are METFORMIN, AMLODIPINE, and LINEZOLID.
1,952
Total Reports
217
Drugs Involved
387
Deaths
1,530
Hospitalizations
53.2 yrs
Average Patient Age
51.4% / 48.6%
Female / Male
Which Drugs Cause Hyperlactacidaemia Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METFORMIN | 807 | 0.9% | 111 | 702 | 249 |
| AMLODIPINE | 105 | 0.2% | 20 | 92 | 76 |
| LINEZOLID | 105 | 0.6% | 23 | 46 | 10 |
| ACETAMINOPHEN | 96 | 0.1% | 19 | 68 | 43 |
| QUETIAPINE | 68 | 0.1% | 17 | 64 | 25 |
| IBUPROFEN | 55 | 0.1% | 1 | 36 | 14 |
| METHYLPREDNISOLONE | 54 | 0.1% | 9 | 38 | 25 |
| LANSOPRAZOLE | 52 | 0.1% | 20 | 32 | 31 |
| NOREPINEPHRINE | 52 | 1.0% | 31 | 20 | 22 |
| MIRTAZAPINE | 46 | 0.2% | 9 | 39 | 46 |
| LORAZEPAM | 44 | 0.1% | 8 | 41 | 41 |
| GLICLAZIDE | 43 | 0.7% | 0 | 35 | 12 |
| ALBUTEROL | 42 | 0.0% | 0 | 29 | 3 |
| SULFAMETHOXAZOLE\TRIMETHOPRIM | 41 | 0.1% | 27 | 20 | 2 |
| FLUOXETINE | 38 | 0.1% | 1 | 38 | 35 |
| HYDROCHLOROTHIAZIDE | 38 | 0.2% | 0 | 38 | 34 |
| PROPOFOL | 38 | 0.2% | 24 | 8 | 4 |
| TACROLIMUS | 38 | 0.0% | 31 | 18 | 8 |
| DIVALPROEX | 36 | 0.3% | 0 | 22 | 21 |
| IRBESARTAN | 36 | 0.4% | 0 | 35 | 3 |