Does METFORMIN Cause Ketoacidosis? 658 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 658 reports of Ketoacidosis have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.7% of all adverse event reports for METFORMIN.
658
Reports of Ketoacidosis with METFORMIN
0.7%
of all METFORMIN reports
56
Deaths
435
Hospitalizations
How Dangerous Is Ketoacidosis From METFORMIN?
Of the 658 reports, 56 (8.5%) resulted in death, 435 (66.1%) required hospitalization, and 208 (31.6%) were considered life-threatening.
Is Ketoacidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 658 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Ketoacidosis?
EMPAGLIFLOZIN (1,411)
DAPAGLIFLOZIN (803)
CANAGLIFLOZIN (641)
INSULIN GLARGINE (231)
INSULIN LISPRO (229)
EMPAGLIFLOZIN\METFORMIN (139)
INSULIN ASPART (123)
DULAGLUTIDE (101)
SEMAGLUTIDE (98)
DAPAGLIFLOZIN PROPANEDIOL\METFORMIN (96)
Which METFORMIN Alternatives Have Lower Ketoacidosis Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN