Does METFORMIN Cause Toe amputation? 103 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 103 reports of Toe amputation have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.1% of all adverse event reports for METFORMIN.
103
Reports of Toe amputation with METFORMIN
0.1%
of all METFORMIN reports
1
Deaths
76
Hospitalizations
How Dangerous Is Toe amputation From METFORMIN?
Of the 103 reports, 1 (1.0%) resulted in death, 76 (73.8%) required hospitalization, and 2 (1.9%) were considered life-threatening.
Is Toe amputation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 103 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Toe amputation?
CANAGLIFLOZIN (2,193)
CANAGLIFLOZIN\METFORMIN (196)
EMPAGLIFLOZIN (149)
INSULIN GLARGINE (133)
ADALIMUMAB (124)
BECAPLERMIN (102)
ETANERCEPT (100)
METHOTREXATE (84)
TOCILIZUMAB (66)
DAPAGLIFLOZIN (64)
Which METFORMIN Alternatives Have Lower Toe amputation Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN