Does METFORMIN Cause Tubulointerstitial nephritis? 328 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 328 reports of Tubulointerstitial nephritis have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.4% of all adverse event reports for METFORMIN.
328
Reports of Tubulointerstitial nephritis with METFORMIN
0.4%
of all METFORMIN reports
6
Deaths
155
Hospitalizations
How Dangerous Is Tubulointerstitial nephritis From METFORMIN?
Of the 328 reports, 6 (1.8%) resulted in death, 155 (47.3%) required hospitalization, and 29 (8.8%) were considered life-threatening.
Is Tubulointerstitial nephritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 328 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Tubulointerstitial nephritis?
OMEPRAZOLE (4,809)
ESOMEPRAZOLE (4,024)
LANSOPRAZOLE (3,860)
PANTOPRAZOLE (3,590)
DEXLANSOPRAZOLE (2,177)
RABEPRAZOLE (1,125)
PEMBROLIZUMAB (860)
IBUPROFEN (844)
VANCOMYCIN (523)
TACROLIMUS (486)
Which METFORMIN Alternatives Have Lower Tubulointerstitial nephritis Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN