Tubulointerstitial nephritis: Which Medications Cause It? (15,220 Reports Across 531 Drugs)
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Tubulointerstitial nephritis has been reported as an adverse event with 531 different drugs in the FDA's FAERS database, with 15,220 total reports. 963 of these reports resulted in death.The drugs most commonly associated with Tubulointerstitial nephritis are OMEPRAZOLE, ESOMEPRAZOLE, and LANSOPRAZOLE.
15,220
Total Reports
531
Drugs Involved
963
Deaths
7,166
Hospitalizations
55.5 yrs
Average Patient Age
48.2% / 51.8%
Female / Male
Which Drugs Cause Tubulointerstitial nephritis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| OMEPRAZOLE | 4,809 | 5.5% | 551 | 1,058 | 130 |
| ESOMEPRAZOLE | 4,024 | 5.3% | 530 | 675 | 44 |
| LANSOPRAZOLE | 3,860 | 6.3% | 569 | 504 | 28 |
| PANTOPRAZOLE | 3,590 | 4.6% | 477 | 707 | 73 |
| DEXLANSOPRAZOLE | 2,177 | 9.1% | 347 | 178 | 4 |
| RABEPRAZOLE | 1,125 | 9.9% | 323 | 105 | 1 |
| PEMBROLIZUMAB | 860 | 1.0% | 30 | 554 | 62 |
| IBUPROFEN | 844 | 1.0% | 6 | 589 | 48 |
| VANCOMYCIN | 523 | 1.5% | 18 | 367 | 40 |
| TACROLIMUS | 486 | 0.5% | 21 | 198 | 18 |
| NIVOLUMAB | 467 | 0.5% | 30 | 285 | 40 |
| CARBOPLATIN | 439 | 0.5% | 15 | 278 | 27 |
| CIPROFLOXACIN | 427 | 1.0% | 30 | 317 | 50 |
| PEMETREXED | 411 | 1.8% | 4 | 253 | 8 |
| PREDNISONE | 374 | 0.2% | 15 | 139 | 10 |
| ACETAMINOPHEN | 359 | 0.3% | 1 | 210 | 23 |
| FUROSEMIDE | 348 | 0.7% | 2 | 168 | 13 |
| MESALAMINE | 329 | 1.7% | 2 | 82 | 3 |
| METFORMIN | 328 | 0.4% | 6 | 155 | 29 |
| ESOMEPRAZOLE\NAPROXEN | 315 | 5.5% | 56 | 19 | 0 |