Does PEMETREXED Cause Tubulointerstitial nephritis? 411 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 411 reports of Tubulointerstitial nephritis have been filed in association with PEMETREXED (Pemetrexed). This represents 1.8% of all adverse event reports for PEMETREXED.
411
Reports of Tubulointerstitial nephritis with PEMETREXED
1.8%
of all PEMETREXED reports
4
Deaths
253
Hospitalizations
How Dangerous Is Tubulointerstitial nephritis From PEMETREXED?
Of the 411 reports, 4 (1.0%) resulted in death, 253 (61.6%) required hospitalization, and 8 (1.9%) were considered life-threatening.
Is Tubulointerstitial nephritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 411 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Tubulointerstitial nephritis?
OMEPRAZOLE (4,809)
ESOMEPRAZOLE (4,024)
LANSOPRAZOLE (3,860)
PANTOPRAZOLE (3,590)
DEXLANSOPRAZOLE (2,177)
RABEPRAZOLE (1,125)
PEMBROLIZUMAB (860)
IBUPROFEN (844)
VANCOMYCIN (523)
TACROLIMUS (486)
Which PEMETREXED Alternatives Have Lower Tubulointerstitial nephritis Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE