Does PEMETREXED Cause Pancytopenia? 1,236 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,236 reports of Pancytopenia have been filed in association with PEMETREXED (Pemetrexed). This represents 5.3% of all adverse event reports for PEMETREXED.
1,236
Reports of Pancytopenia with PEMETREXED
5.3%
of all PEMETREXED reports
286
Deaths
861
Hospitalizations
How Dangerous Is Pancytopenia From PEMETREXED?
Of the 1,236 reports, 286 (23.1%) resulted in death, 861 (69.7%) required hospitalization, and 127 (10.3%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 1,236 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
Vomiting (903)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which PEMETREXED Alternatives Have Lower Pancytopenia Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE