METHADONE for Drug withdrawal maintenance therapy: Side Effects & Safety Data
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There are 559 adverse event reports in the FDA FAERS database where METHADONE was used for Drug withdrawal maintenance therapy.
Most Reported Side Effects for METHADONE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug dependence | 5,739 | 21.8% | 660 | 656 |
| Toxicity to various agents | 4,586 | 17.5% | 3,639 | 917 |
| Drug abuse | 4,480 | 17.1% | 3,038 | 916 |
| Overdose | 3,472 | 13.2% | 1,240 | 553 |
| Pain | 2,754 | 10.5% | 71 | 242 |
| Death | 2,716 | 10.3% | 2,714 | 108 |
| Emotional distress | 2,388 | 9.1% | 44 | 67 |
| Drug withdrawal syndrome | 2,127 | 8.1% | 82 | 350 |
| Foetal exposure during pregnancy | 1,759 | 6.7% | 78 | 288 |
| Drug withdrawal syndrome neonatal | 1,458 | 5.6% | 49 | 238 |
| Anxiety | 941 | 3.6% | 38 | 175 |
| Dependence | 883 | 3.4% | 139 | 27 |
| Developmental delay | 845 | 3.2% | 11 | 36 |
| Drug ineffective | 845 | 3.2% | 51 | 381 |
| Somnolence | 816 | 3.1% | 197 | 313 |
Other Indications for METHADONE
Product used for unknown indication (16,426)
Pain (1,814)
Cancer pain (827)
Drug dependence (746)
Drug use disorder (512)
Back pain (267)
Drug abuse (255)
Foetal exposure during pregnancy (140)
Neuralgia (123)
Product substitution (112)
Other Drugs Used for Drug withdrawal maintenance therapy
NICOTINE (287)
BUPRENORPHINE (177)
BUPRENORPHINE\NALOXONE (114)
MORPHINE (24)
GUANFACINE (18)
LOPERAMIDE (14)
LEVOMETHADONE (12)
HYDROMORPHONE (10)
CLONIDINE (9)
DIAZEPAM (6)