Does METHADONE Cause Dependence? 883 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 883 reports of Dependence have been filed in association with METHADONE (METHADONE HYDROCHLORIDE). This represents 3.4% of all adverse event reports for METHADONE.
883
Reports of Dependence with METHADONE
3.4%
of all METHADONE reports
139
Deaths
27
Hospitalizations
How Dangerous Is Dependence From METHADONE?
Of the 883 reports, 139 (15.7%) resulted in death, 27 (3.1%) required hospitalization, and 3 (0.3%) were considered life-threatening.
Is Dependence Listed in the Official Label?
Yes, Dependence is listed as a known adverse reaction in the official FDA drug label for METHADONE.
What Other Side Effects Does METHADONE Cause?
Drug dependence (5,739)
Toxicity to various agents (4,586)
Drug abuse (4,480)
Overdose (3,472)
Pain (2,754)
Death (2,716)
Emotional distress (2,388)
Drug withdrawal syndrome (2,127)
Foetal exposure during pregnancy (1,759)
Drug withdrawal syndrome neonatal (1,458)
What Other Drugs Cause Dependence?
ACETAMINOPHEN\HYDROCODONE (28,841)
ACETAMINOPHEN\OXYCODONE (26,147)
OXYMORPHONE (8,816)
TRAMADOL (8,530)
MORPHINE (5,656)
FENTANYL (4,358)
ACETAMINOPHEN\CODEINE (3,857)
CODEINE\PROMETHAZINE (3,521)
HYDROCODONE\IBUPROFEN (3,304)
PROPOXYPHENE (3,206)
Which METHADONE Alternatives Have Lower Dependence Risk?
METHADONE vs METHAMPHETAMINE
METHADONE vs METHENAMINE HIPPURATE
METHADONE vs METHIMAZOLE
METHADONE vs METHOCARBAMOL
METHADONE vs METHOHEXITAL