Does MITOTANE Cause Hyponatraemia? 30 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 30 reports of Hyponatraemia have been filed in association with MITOTANE (Lysodren). This represents 3.0% of all adverse event reports for MITOTANE.
30
Reports of Hyponatraemia with MITOTANE
3.0%
of all MITOTANE reports
1
Deaths
9
Hospitalizations
How Dangerous Is Hyponatraemia From MITOTANE?
Of the 30 reports, 1 (3.3%) resulted in death, 9 (30.0%) required hospitalization, and 10 (33.3%) were considered life-threatening.
Is Hyponatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MITOTANE. However, 30 reports have been filed with the FAERS database.
What Other Side Effects Does MITOTANE Cause?
Nausea (210)
Fatigue (205)
Off label use (154)
Diarrhoea (123)
Vomiting (97)
Drug ineffective (86)
Decreased appetite (77)
Adrenal insufficiency (76)
Dizziness (76)
Asthenia (70)
What Other Drugs Cause Hyponatraemia?
FUROSEMIDE (3,127)
HYDROCHLOROTHIAZIDE (2,138)
OMEPRAZOLE (1,635)
LANSOPRAZOLE (1,416)
SERTRALINE (1,332)
RAMIPRIL (1,178)
SPIRONOLACTONE (1,166)
PANTOPRAZOLE (1,134)
INDAPAMIDE (976)
AMLODIPINE (879)
Which MITOTANE Alternatives Have Lower Hyponatraemia Risk?
MITOTANE vs MITOXANTRONE
MITOTANE vs MITRAGYNINE\HERBALS
MITOTANE vs MIZORIBINE
MITOTANE vs MOBOCERTINIB
MITOTANE vs MOCLOBEMIDE