MITOXANTRONE for Premedication: Side Effects & Safety Data
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There are 15 adverse event reports in the FDA FAERS database where MITOXANTRONE was used for Premedication.
Most Reported Side Effects for MITOXANTRONE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 668 | 16.0% | 87 | 403 |
| Off label use | 368 | 8.8% | 82 | 142 |
| Neutropenia | 296 | 7.1% | 76 | 144 |
| Drug ineffective | 293 | 7.0% | 79 | 119 |
| Thrombocytopenia | 256 | 6.1% | 66 | 128 |
| Sepsis | 240 | 5.8% | 94 | 98 |
| Pyrexia | 214 | 5.1% | 46 | 125 |
| Product use in unapproved indication | 177 | 4.3% | 53 | 58 |
| Disease progression | 173 | 4.2% | 58 | 42 |
| Acute myeloid leukaemia | 167 | 4.0% | 78 | 43 |
| Pneumonia | 157 | 3.8% | 76 | 71 |
| Infection | 153 | 3.7% | 72 | 37 |
| Pancytopenia | 148 | 3.6% | 24 | 57 |
| Myelodysplastic syndrome | 139 | 3.3% | 35 | 25 |
| Septic shock | 133 | 3.2% | 57 | 98 |
Other Indications for MITOXANTRONE
Acute myeloid leukaemia (1,248)
Acute lymphocytic leukaemia (414)
Diffuse large b-cell lymphoma (201)
Product used for unknown indication (183)
Acute promyelocytic leukaemia (158)
B-cell lymphoma (125)
Multiple sclerosis (112)
Non-hodgkin's lymphoma (104)
B-cell type acute leukaemia (101)
Acute lymphocytic leukaemia recurrent (89)
Other Drugs Used for Premedication
METHYLPREDNISOLONE (2,339)
DIPHENHYDRAMINE (2,227)
ACETAMINOPHEN (1,611)
ONDANSETRON (1,101)
DEXAMETHASONE (786)
DEXCHLORPHENIRAMINE (565)
RANITIDINE (564)
HYDROCORTISONE (443)
CETIRIZINE (363)
APREPITANT (339)